中国林科院亚热带林业研究所基本科研业务费
DNA甲基化是主要发生在CpG双核苷酸序列中的胞嘧啶上的一种表面遗传修饰。它以S-腺苷甲硫氨酸为甲基供体,在DNA甲基酶的催化下,将甲基转移到胞嘧啶上,生成5-甲基胞嘧啶。DNA甲基化在植物的很多生命过程中具有重要的作用。本文就其作用机制、主要研究应用以及未来的前景进行简单阐述,从而为DNA甲基化在植物遗传学研究中的研究提供理论参考。
DNA Methylation,most occurs in CpG dinucleotides, is a kind of epigenetic modification,most occurs in CpG dinucleotides。 The most striking feature of DNA methylation patterns is that the addition of a methyl group at the 5-position of cytosine in CpG dinucleotides by DNA methytransferase. It take for S-adenosylmethionine as methyl donor. DNA methylation has essential roles in many plant life processes. The characteristics of plant methylation,its regulating mechanisms, the effects on plants and the application of DNA methylation will be reviewed in this paper, providing a theoretical references to DNA methylation research on plant genetics.
郭广平,袁金铃,顾小平. DNA甲基化在植物研究中的应用现状与前景[J].植物遗传资源学报,2011,12(3):425-430.
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