Maize Stalk rot is one of the important diseases, which are occurring in corn cultivating regions of China and abroad. Due to increasing mechanical harvesting and grain direct harvest, stalk rot has become the most threatening disease in maize production. The cultivation of resistant varieties is the most economic and effective measure to control stalk rot. This paper reviews the research progress of stalk rot on aspects of the distributing regions, pathogenic species, resistant germplasm screening, resistance inheritance and disease resistance gene discovery and localization, which will lay an important theoretical foundation for IPM of this disease.