In order to systematically understand the current status on the character diversity of wheat varieties from different origins （southern part and northern part） in Huang-Huai winter wheat region， 109 newly-released varieties from this region were investigated in this study. The character diversity analysis and comprehensive evaluation based on 12 agronomic and quality traits were carried out by using Shannon-Wiener diversity index （H′?）， cluster analysis， principal component analysis， regression model construction， etc. 84 and 25 varieties were collected from the southern and northern part of Huang-Huai winter wheat region， accounting for 77.1% and 22.9%， respectively. The wheat varieties showing strong gluten and medium strong gluten accounted for 11.9% and 16.5% respectively， accounting for 28.4% in total. The variation coefficient on 12 traits ranged from 1.66% to 76.64%， with an average of 11.37%. The variation coefficient of stabilization time was the largest， and the variation coefficient of bulk density was the smallest. The H′ index on 12 traits ranged from 1.50 to 4.65， with an average of 3.78. The H′ index on basic seedling was the smallest （1.50）， and the rest H′ were above 3.00. The H′ on 12 traits of wheat in the northern part was higher than that in the southern part， with an increase of 24.7%-188.6%. The increase of growth period was the smallest， and the increase of basic seedling was the largest. At the square Euclidean distance of 10.0， 109 wheat varieties were grouped into six categories， mostly being coincidence with their origins. There were significant or extremely significant differences in bulk density， growth period， spike number and water absorption rate of wheat varieties from different origins， part which were 0.9%， 3.5%， 11.0% and 4.1% lower in the southern than that in the northern， respectively. The cumulative contribution rates of the first six principal components of wheat varieties from different origins had little difference， with 80.25% in the southern part and 83.33% in the northern part. The comprehensive scores of wheat varieties from different origins were strong gluten wheat > medium strong gluten and medium gluten wheat. The richness and uniformity of wheat traits in the northern part were higher than those in the southern part， and the evolutionary potential was higher. The five traits of spike number， grain number per spike， bulk density， protein content and water absorption rate could be used to evaluate the comprehensive performance of northern part wheat varieties. Gained from these results， it is suggested that future improvement of wheat varieties in the southern part would profile from enlarging the genetic basis. The six traits including growth period， spike number， yield， bulk density， protein content and wet gluten content could be used to evaluate the comprehensive performance of wheat varieties in this region.