Callus induction is crucial for successful genetic transformation， while WOX genes might enhance this process by stimulating cell division and shoot organogenesis. This study systematically analyzed the WOX gene family in common bean （Phaseolus vulgaris L.）， resulting in identification of 18 WOX genes that encode proteins with 177 to 847 amino acids. These proteins are predicted containing homeodomain conserved domains and to be localized in the cell nucleus. The promoters were identified containing cis-acting elements related to meristem formation and auxin response. A collinearity and phylogenetic tree analysis was conducted with the members of the WOX gene family in mung bean， soybean and Arabidopsis thaliana. The 124 WOX genes can be divided into three major groups， and the WOX homologous genes among the four species are subject to purifying selection. Through screening the media with different concentrations of 6-BA and 2，4-D hormone ratios， the callus induction systems of two common bean varieties were successfully established. Through transcriptome combined with qRT-PCR analysis， eight differentially expressed WOX genes were identified. The PvWOX1， PvWOX15 and PvWOX16 genes were significantly correlated with the callus induction rate， and their transcriptional trends were further confirmed using qRT-PCR. These results indicate that the PvWOX1， PvWOX15 and PvWOX16 genes can be used as potential target genes for improving the genetic transformation efficiency in common bean.