This study employed non-targeted metabolomics to analyze the differential metabolic responses of the wild onion species Allium przewalskianum Regel to salt stress （NaCl）， drought stress （PEG）， and combined salt-drought stress （NaCl_PEG）， with the aim of elucidating its adaptation mechanisms. The experiment design included four treatments： a pure water control， 240 mmol/L NaCl stress， 12% PEG-6000 drought stress， and a combined stress of 240 mmol/L NaCl+12% PEG-6000. Metabolite profiling was conducted using ultra-performance liquid chromatography-mass spectrometry （UPLC-MS）. Subsequent analyses including Principal Component Analysis （PCA）， volcano plots， hierarchical clustering， Venn diagrams， and KEGG pathway enrichment， identified 622 differentially accumulated metabolites （DAMs）. The results showed that combined stress induced the most severe perturbation in the metabolic network of A. przewalskianum， with a great number of DAMs （331） compared to salt stress （185） and drought stress （212）. Fatty acids and terpenoids were identified as the major metabolite classes responsive to stress. Notably， 52 fatty acids were upregulated under combined stress， highlighting their role in osmoregulation. Among the top 20 metabolites with the highest variation， flavan-3-ols and oleanane-type triterpenoids participated in stress adaptation through antioxidant activity， signal transduction （e.g.， cross-pathway regulation by NAE（16∶1））， and defense functions. KEGG enrichment analysis revealed distinct pathway responses： salt stress affected nucleotide metabolism； drought stress primarily involved glyoxylate and carbon metabolism； while combined stress activated ABC transporters and amino acid biosynthesis. K-Means clustering identified a subset of 100 metabolites exhibiting gradual upregulation specifically under combined stress， suggesting synergistic response mechanisms. This study provides the first characterization of the metabolic responses of this species to multiple abiotic stresses. The key metabolites （e.g.， fatty acids， terpenoids） and pathways （e.g.， ABC transporters） offer newl targets for elucidating molecular resistance mechanisms. These findings provide a theoretical basis for improving cultivation practices and enhancing stress resistance breeding of characteristic Allium plant resources on the Qinghai-Tibet Plateau.