The identification of QTL facilitates may reveal the molecular base of many important agronomic traits and conduct efficient molecular breeding for these traits in order to increase crop productivity. In recent years, the breakthrough was made in the map-based cloning for QTLs of crops and a batch of QTLs were successfully isolated. The rapid progresses in the genomics of model plants have provided the new strategies and methods for the map-based cloning for crop QTLs. This presentation reviews the status and trend in relative researches.