Brown planthopper (BPH, Nilaparvata lugens Stål) is one of main insect pests of rice (Oryza sativa L.). The most scientific and safest measure of breeding BPH resistant cultivars is identification and using BPH resistance genes. In this study, HS204 that carries a dominant gene for resistance to BPH was used as the resistance donor, and the restorer lines Minghui 65, 582, and MR were used as the recurrent parent. By means of backcrossing, seedling detection, and selection of agronomic traits at adult stage, the gene for resistance to BPH was transferred into the recurrent parent, resulting in 45 homozygous resistant lines. The combining ability, grain quality, and other agronomic traits were also improved accordingly.