Abstract:The wheat cultivar Norin 89, also known as “Xiao Yingsu”, was derived from Norin 10 successfully. That was an important breakthrough in wheat breeding for drought-resistance and high-yield. The wheat cultivar Lumai 13 achieved a yield record of 9 244.5kg/hm2 under non-irrigated conditions . The wheat cultivar Lumai 14 had the largest acreage in the Yellow and Huai River Valley Winter Wheat Region (YHRVWWR) in the early years of 1990s. Both Lumai 13 and Lumai 14 are of high yield, multi-resistance, and wide adaptation. They were also elite parents widely used by many wheat breeders. Forty-nine elite wheat cultivars,which have been derived from Lumai 13 or Lumai 14,are now widely grown in the YHRVWWR and produced huge economic and social benefits. Thus it was suggested that the innovation of wheat germplasm is very important for a successful wheat breeding program and for the national food safety .