Traditional breeding is a method to develop new varieties through genetic recombination and phenotype selection based on sexual hybridization. With the gradual reduction of genetic diversity of the varieties used, the bottleneck of traditional breeding becomes more and more obvious, and it is difficult to develop a breakthrough variety with conventional breeding technology. The innovation of biotechnology has greatly promoted the development of modern breeding. With the rapid progress in multiple biological disciplines, including molecular biology, genomics, systems biology, synthetic biology, has led to the innovation of design