Uvaria kweichowensis is a native plant species in China， and the wild populations are relatively small with narrowed geographic distribution. In order to systematically understand its quantity， distribution status and utilization in Guangxi province， we carried out the investigation and collection of Uvaria kweichowensis germplasm resources in nine counties through field visits and questionnaire surveys， and a total of 95 Uvaria kweichowensis samples were collected from 2016 to 2022. The survey results show that Uvaria kweichowensis is a perennial vine with mature leaf leathery， being mainly distributed in the karst rocky mountain area with the attitude of 650 to 1100 meters in nine counties such as Longan County and Tiane County in Guangxi. The number of germplasm resources in wild populations were scarce， and individuals often grew individually without protection. The local people have the traditional habit to collect the leaves of Uvaria kweichowensis for diseases treatment and tea drinking. In addition， we deployed the seed sowing or branch cottage， in order to collect and select the elite germplasm resources. The results showed that low survival rate of Uvaria kweichowensis， the germination rate of seeds from different sources was 25.7 % -34.4 %， and the survival rate of cuttings was 4.4%-14.4%. Collectively， this study discussed the main factors harmful to this species and the solution for protection of Uvaria kweichowensis， which might provide the reference for the protection， excavation and innovative utilization of the germplasm resources of Uvaria kweichowensis in Guangxi province， China.