Abstract: Kernel weught is a key factor influencing wheat processing quality ,which is determined by quantitative trait loci(QTL). In the present paper, recombinant inbred lines(RIL) population was used derived from 6044?1-35. The results showed that sixteen QTLs of kernel weight were detected in different seed filling periods totally. One QTL of kernel weight per spike detected in 10 days after flowering was an important one, which was on chromosome 2A and actcounted for 12%, and its genetic effect is more than 10. QTLs of thousand kernel weight were detected in the seven periods. One QTL of thousand kernel was detected 10 days after flowering which was on chromosome 2A, the interval from Xgwm448 to Xgpw7399 and explained 18% of phenotypic variance. One QTL was detected 15 days after flowering which was on chromosome2A, the interval from Xgwm448 to Xgpw7399 and explained 5% of phenotypic variance. Two QTLs of thousand kernel was detected 20 days after flowering which was on chromosome 2A, the interval from Xgwm448 to Xgpw7399 and Xgwm372 to Xgwm95 explained 5% and 4% of phenotypic variance. Three QTLs of thousand kernel was detected 25 days after flowering which was on chromosome 4A, the interval from Xgpw2228 to Xwmc501, and chromosome 2A, Xgwm372 to Xgwm95 and Xgwm448 to Xgpw7399, explained 2%, 4% and 8% of phenotypic variance. One QTL of thousand kernel was detected 30 days after flowering which was on chromosome 2A, the interval from Xgwm448 to Xgpw7399 and explained 3% of phenotypic variance. One QTL of thousand kernel was detected 35 days after flowering which was on chromosome 2A, the interval from Xgwm448 to Xgpw7399 and explained 3% of phenotypic variance. Two QTLs of thousand kernel was detected 40 days after flowering which was on chromosome 1D, the interval from Xwmc93 to Xgpw2224 and chromosome 2A, the interval from Xgwm448 to Xgpw7399 explained 1% and 5% of phenotypic variance. QTLs of thousand kernel weight mostly located in linkage group 2A, the interval from Xgwm448 to Xgpw7399, which was a rich domain on QTLs.