Mentana is one of the backbone parents in wheat breeding of our country. In order to investigate the contribution of Mentana in quality breeding, the HMW-GS composition and evolution of Mentana and its derivations were analyzed by SDS-PAGE. The results showed that the HMW-GS composition of Mentana was N/7 8/2 12 and its quality score was 7. The average quality score of the derivations was 7.62, which was high than Mentana.45.45% was carried the same HMW-GS with Mentana in derivations, and N/7 8/2 12 was dominant HMW-GS compound in every generation. The heredity of HMW-GS for Mentana from first to forth generation was very well, the frequency of N, 7 8, and 2 12 were high than 50%, and the highest was 100%. 12 varieties extended in large areas derived from Mentana had merit of high yield, adaptability, and resistance, which were same with Mentana. The results above indicated that the backbone parent Mentana contributed little to its derivations in quality, but probably lot in stripe rust resistance and high yield potential.