FBN 11 gene, a member of fibrillin gene family, is one of the important members of the FBN family of proteins in plastids of plants. It has the 300-500 amino acid residues longer than do other members in this family, suggesting its specific functions in higher plants. In this study, the full-length cDNA of a OsFBN11 gene regulated by abiotic stresses in rice seedlings was cloned and analyzed, it was found to contain 12 introns and 13 exons, and can encode a protein with M.W. 72.4 kDa, the pI value 9.3. Bioinformatics analysis showed that, this protein contains a random-coil, alpha helix and extended strand, does not contain a transmembrane domain, and is also highly hydrophilic. PSORT software predicted this protein may be localized in chloroplast. Analyses of FBN11 protein homologies in 14 plant species and conserved domains in 5 plant species showed that, this protein has a typical PAP-Fibrillin domain and PKc kinase domain. The whole growth period rice chip analysis showed that OsFBN11 gene is highly expressed in callus, leaves and root tissues. RT-PCR detection showed that OsFBN11 gene expressions were induced by ABA, NaCl and drought stress treatments in rice seedlings. These results above show that OsFBN11 plays an important role in the response to plastid development and abiotic stress in rice.