“Agro-biological Resources Investigation in Guizhou Province” is one of National Science and Technology Fundamental Projects. According to the project requirements, we have implemented the general investigation in 42 counties and the systematic investigation in 21 counties. Through the co-efforts of many research institutes in the past 5 years, Agro-biological resources in Guizhou have been identified and more than 4800 samples have been collected, in which over 150 rich germplasm resources have been screened from disease resistance, stress resistance, superior quality, early-maturing, high productive and other aspects. The rich germplasm resources is imbued with use value of important and can be used for crop breeding and basic research, we ought to strengthen use and conservation.