Soybean （Glycine max （L.） Merr.） is an important oil crop and is often challenged by multiple stresses，thus resulting in loss of yield production and decrease of grain quality in lifecycle. WRKY transcription factors （TFs） are identified to involve into the responses to various stresses，for instance by regulating phytohormone-mediated signal transduction. The WRKY transcription factors belong to one of the TFs families found in plants. The family member generally contains one or two WRKY domain（s） which consists of approximately 60 amino acids. WRKY-TFs have been uncovered participating into the biological processes such as crop senescence， seed development，germination and dormancy，and have been also found to regulate the adaptability of plants response upon biotic and abiotic stresses. However，deciphering WRKY-TFs in soybean remains relatively insufficient. This study mainly elaborates on the research progress of the family structure/organization and their roles responding to biotic and abiotic stresses. Moreover，we propose future research focuses and hot spots to provide insights for unlocking the biological function of the WRKY family members in soybean.