Nangeng 46 is a high-quality japonica rice variety developed by Jiangsu Academy of Agricultural Sciences and this variety shows good eating quality， resistance to stripe disease， and high yield. This study investigated a series of rice varieties derived from Nangeng 46 regarding to agronomic traits including yield， quality and disease resistance. Their allelotypes of important functional genes were genotyped based on single nucleotide polymorphism （SNP） markers. As the first good eating quality japonica variety in the middle and downstream valley of the Yangtze River， Nangeng 46， which serves as the parental line in the breeding programs， supported the development of 29 varieties in provinces Shanghai， Anhui， Hubei， Jiangsu， Liaoning， and Hebei， by 2022. The obvious variations on the appearance quality， physicochemical characteristics of grain and starch viscosity characteristics were observed among the offspring varieties， while the variations on the growth period， plant height， yield and processing quality were rather minor. The allelic analysis of important functional genes showed that Wx was the main gene affecting the taste of derived varieties rice. Along with the increase in the number of quality genes with different alleles from Nangeng 46， the taste quality gradually decreased. In the future， the breeding programs using Nangeng 46 as the parent， we would like to suggest the selection with attention on appearance quality， grain physicochemical characteristics and starch viscosity characteristics. In addition， the deployment and complementarity of blast resistance genes should draw an attention in the future.