The high molecular weight glutenin subunits （HMW-GS） compositions and the quality parameters in 184 Sichuan wheat varieties （released from 1949 to 2018）， one introduced variety and two landraces were analyzed. The results showed that there were three alleles at Glu-1A including 1， N， 2*， eight at Glu-1B including 7， 20， 22， 7+8， 7+9， 6+8， 14+15 and 23+18， and three at Glu-1D including 5+10， 2+12 and 3.1^t+11*^t. These subunits on sub-genomes A， B， D formed 23 allele combinations， and the combination （N/7+9/5+10） was found with a frequency of 12.3%. Taking advantage of breeding effects， the allele diversity at the Glu-1 locus， as well as the ratio of high-quality strong gluten 1 （Glu-1A） and 5+10 （Glu-1D） were gradually increased. The medium-weak gluten wheat varieties were found with predominant proportion in Sichuan province. The increase on test weight and sedimentation value， but the increase followed by decreased on other quality traits were observed. This study can provide reference for further improvement of wheat quality in Sichuan province， China.